Robert Hoehndorf
Robert Hoehndorf is a computer scientist whose research on knowledge representation and neuro-symbolic methods is applied to the life sciences. After a 2009 PhD at Leipzig University and research posts in the UK at Aberystwyth University, the University of Cambridge and the European Bioinformatics Institute, he joined KAUST in 2014 and was promoted to associate professor in 2020. His group developed the DeepGO methods for protein function prediction, from the 2017 DeepGO classifier to DeepGO-SE, which appeared in Nature Machine Intelligence in 2024. In 2022, he became Editor in Chief of the Journal of Biomedical Semantics and Interim Associate Director of KAUST's Computational Bioscience Research Center. He is an associate professor of computer science at KAUST and principal investigator of its Bio-Ontology Research Group.
- Now at
- King Abdullah University of Science and Technology and Computational Bioscience Research Center
Timeline
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2005–2009
Computer science at Leipzig
He earns a Diplom-Informatiker degree in computer science at Leipzig University in 2005 and a PhD in computer science there in 2009.
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2009–2014
UK posts and PhenomeNET
He works in the UK as a research fellow at Aberystwyth University, a research associate at the University of Cambridge, and a postdoctoral fellow at the European Bioinformatics Institute. In 2011, he publishes PhenomeNET in Nucleic Acids Research with Paul Schofield and Georgios Gkoutos, a cross-species network of phenotypic similarity between genotypes and diseases.
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2014
Assistant professor at KAUST
He joins King Abdullah University of Science and Technology (KAUST) in 2014 as an assistant professor of computer science.
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2017
The DeepGO classifier
In 2017, he coauthors DeepGO with Maxat Kulmanov and Mohammed Asif Khan in the journal Bioinformatics. The deep learning model combines protein sequences with a cross-species protein–protein interaction network and shows a significant improvement over BLAST for predicting cellular locations.
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2020
Promotion to associate professor
KAUST promotes him from assistant to associate professor in 2020, after a year-long review of his scientific and scholarly output. His Bio-Ontology Research Group, based in the Computational Bioscience Research Center, primarily works on finding variants in genomes that cause disease.
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2022
Journal editor and center leader
In 2022, he becomes Editor in Chief of the Journal of Biomedical Semantics, is elected a Bye Fellow at Robinson College, University of Cambridge, and is named a Leibniz AI Fellow at Leibniz University of Hannover. In September 2022, he also becomes Interim Associate Director of KAUST's Computational Bioscience Research Center.
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2024
DeepGO-SE in Nature Machine Intelligence
In February 2024, Nature Machine Intelligence publishes DeepGO-SE, built with Maxat Kulmanov, Stefan Arold and coauthors under his supervision. The method predicts Gene Ontology functions from protein sequences with a pretrained language model and ranks in the top 20 of more than 1,600 algorithms in an international function prediction competition.
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As of October 2026
Associate professor at KAUST
He is an associate professor of computer science at KAUST and principal investigator of its Bio-Ontology Research Group, whose work centers on knowledge representation and neuro-symbolic methods in the life sciences. Since 2021, he is also Track Leader of the Bioinformatics & Machine Learning Track in KAUST's Bioengineering Program.
Career
- Since 2014King Abdullah University of Science and TechnologyAssistant Professor of Computer Science, Interim Associate Director
- NowComputational Bioscience Research CenterPrincipal Investigator
- From 2022University of CambridgeResearch Associate, Bye Fellow
- Aberystwyth UniversityResearch Fellow
- European Molecular Biology LaboratoryPostdoctoral Fellow
Education
- 2009Leipzig UniversityDiplom-Informatiker and PhD in computer science
Sources and credits
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- Robert Hoehndorf | Associate Professor, Computer Science | Computer, Electrical and Mathematical Sciences and Engineering
- PhenomeNET: a whole-phenome approach to disease gene discovery - PMC
- Appointment of Prof. Xin Gao as Interim Director and Prof. Robert Hoehndorf as Interim Associate Director of CBRC
- DeepGO: predicting protein functions from sequence and interactions using a deep ontology-aware classifier - PMC
- Robert Hoehndorf promoted to associate professor at KAUST
- Protein function prediction as approximate semantic entailment | Nature Machine Intelligence
- AI Unveils Mysteries of Unknown Proteins' Functions - Neuroscience News