Olga Vrousgou
Olga Vrousgou is a researcher whose work spans biomedical data resources, distributed ledgers and language-model training. Her publications cover ontology tools, Open Targets and the NHGRI-EBI GWAS Catalog. She later coauthored CCF and IA-CCF papers, studied contextual bandits with feedback graphs, and coauthored AgentInstruct, whose synthetic data was used to produce Orca-3. Her last known role was Senior Software Engineer at Microsoft Research in January 2024, when she wrote a guide to custom models in AutoGen.
- Works
- 15
- Citations
- 5,203
- h-index
- 6
Publication numbers from OpenAlex, as of 22 October 2026.
Timeline
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2015
A comparative genomics poster
In 2015, she coauthors the poster “Large-scale modular comparative genomics: the Grid approach” with Fotis Psomopoulos and Pericles Mitkas. It is presented at the 23rd Annual International Conference on Intelligent Systems for Molecular Biology.
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2016
Ontology service and Open Targets
In 2016, she coauthors a paper on biomedical ontology evolution in the EMBL-EBI Ontology Lookup Service with Tony Burdett, Helen Parkinson and Simon Jupp; it appears in the EDBT/ICDT 2016 joint conference workshops. Also in 2016, she coauthors the Open Targets platform paper, which describes a data integration and visualization platform that links drug targets with diseases; her affiliations are Open Targets and the European Bioinformatics Institute (EMBL-EBI).
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2018
The NHGRI-EBI GWAS Catalog
In 2018, she coauthors the Nucleic Acids Research paper on the NHGRI-EBI GWAS Catalog. As of September 2018, the Catalog contains 5,687 GWAS and 71,673 variant-trait associations from 3,567 publications.
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April 2019
CCF for confidential blockchains
In April 2019, she coauthors Microsoft Research report MSR-TR-2019-16 with Mark Russinovich and Miguel Castro. The report presents CCF, a framework for building permissioned confidential blockchains.
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2020
Open Targets Genetics
In 2020, she coauthors the Open Targets Genetics paper. The open-access resource aggregates human GWAS and functional genomics data to connect GWAS-associated loci and variants with likely causal genes.
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April 2022
IA-CCF and accountable ledgers
In April 2022, she coauthors IA-CCF, a permissioned ledger system that can assign blame to members who operate misbehaving replicas. Her coauthors include Alex Shamis, Peter Pietzuch, Burcu Canakci, Miguel Castro and Mark Russinovich.
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2023
Contextual bandits with feedback graphs
In February 2023, she coauthors “Practical Contextual Bandits with Feedback Graphs” with Mengxiao Zhang, Yuheng Zhang, Haipeng Luo and Paul Mineiro. The paper reduces contextual bandits with feedback graphs to regression, and its algorithms achieve established minimax rates with practical computation.
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2024
AutoGen and AgentInstruct
Her last known role is Senior Software Engineer at Microsoft Research in January 2024, when she writes a guide to custom-model support in AutoGen. In July 2024, she coauthors “AgentInstruct: Toward Generative Teaching with Agentic Flows,” an agentic framework for creating synthetic post-training data; the paper appears in the Orca project’s publications list. Post-training Mistral-7b on the data yields Orca-3, which improves on Mistral-7b-Instruct across many benchmarks.
Career
- 2016–2020Open Targets
- 2016–2020European Molecular Biology Laboratory
- Microsoft ResearchSenior Software Engineer
Most-cited works
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019
- Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics
- Open Targets: a platform for therapeutic target identification and validationWith Oliver Stegle
- CCF: A Framework for Building Confidential Verifiable Replicated Services
- OLS Client and OLS Dialog: Open Source Tools to Annotate Public Omics Datasets
Sources and credits
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- Large-scale modular comparative genomics: the Grid approach
- CEUR-WS.org/Vol-1558 - Workshops of the EDBT/ICDT 2016 Joint Conference
- Open Targets: a platform for therapeutic target identification and validation - PMC
- The NHGRI-EBI GWAS Catalog of published genome-wide association studies, targeted arrays and summary statistics 2019 - PMC
- CCF: A Framework for Building Confidential Verifiable Replicated Services - Microsoft Research
- Open Targets Genetics: systematic identification of trait-associated genes using large-scale genetics and functional genomics - PMC
- IA-CCF: Individual Accountability for Permissioned Ledgers - Microsoft Research
- [2302.08631] Practical Contextual Bandits with Feedback Graphs
- AutoGen with Custom Models: Empowering Users to Use Their Own Inference Mechanism | AutoGen 0.2
- AgentInstruct: Toward Generative Teaching with Agentic Flows - Microsoft Research
- Orca - Microsoft Research: Publications