Li-wei H. Lehman
Also known as Li-wei Lehman
Lehman is a research scientist at MIT's Institute for Medical Engineering and Science who develops machine learning methods for intensive care, from vital-sign dynamics to treatment-outcome prediction. With a master's degree from the Georgia Institute of Technology and a PhD from MIT, they published a switching-dynamics model of heart rate and blood pressure in 2015, and the G-Net approach to counterfactual treatment prediction in 2021. Their papers won AMIA Distinguished Paper Awards in 2020 and 2024. In 2023, they were among the authors of the MIMIC-IV database paper and first author of the VTaC alarm benchmark at NeurIPS. They lead a project on learning optimal dynamic treatment strategies from observational health data.
Timeline
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2012
Shared dynamics in ICU signals
They hold a master's degree in computer science from the Georgia Institute of Technology and a PhD from MIT. In 2012, they publish "Discovering shared dynamics in physiological signals: Application to patient monitoring in ICU" with Shamim Nemati, Ryan P. Adams and Roger Mark at the IEEE Engineering in Medicine and Biology Society conference in San Diego.
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2015
Vital-sign dynamics and ICU mortality
A paper with Ryan P. Adams, Louis Mayaud, George B. Moody, Atul Malhotra, Roger G. Mark and Shamim Nemati appears in the IEEE Journal of Biomedical and Health Informatics in May 2015. It uses a switching vector autoregressive framework to learn dynamics of heart rate and blood pressure; in an ICU cohort of over 450 patients from the MIMIC II database, the discovered dynamics are significantly associated with hospital mortality.
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2020
An AMIA distinguished paper award
In 2020, the paper "Is Deep Reinforcement Learning Ready for Practical Applications in Healthcare? A Sensitivity Analysis of Duel-DDQN for Sepsis Treatment," written with MingYu Lu, Zachary Shahn, Daby Sow and Finale Doshi-Velez, wins the Distinguished Paper Award at the AMIA Annual Symposium.
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2021–2022
G-Net for counterfactual prediction
In 2021, Lehman and colleagues publish G-Net, a recurrent network approach to g-computation for counterfactual prediction under a dynamic treatment regime, in Machine Learning for Health. In February 2022, Lehman, an MIT-IBM Watson AI Lab project lead, calls G-Net the first deep-learning approach based on g-computation that can predict both population-level and individual-level treatment effects under dynamic and time-varying treatment strategies.
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2023
MIMIC-IV and the VTaC benchmark
In 2023, MIMIC-IV, a publicly available database sourced from the electronic health record of the Beth Israel Deaconess Medical Center, appears in Scientific Data with Lehman among its MIT authors. At NeurIPS 2023, Lehman is first author of VTaC, an annotated benchmark of over 5,000 waveform recordings of ventricular tachycardia alarms triggered by ICU bedside monitors.
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2024
A second AMIA paper award
In March 2024, the paper "Counterfactual Sepsis Outcome Prediction under Dynamic and Time-Varying Treatment Regimes" receives the Clinical Research Informatics Distinguished Paper Award at the AMIA 2024 Informatics Summit. In August 2024, they present G-Transformer, a model for counterfactual outcome prediction under dynamic and time-varying treatment regimes, at the Machine Learning for Healthcare conference in Toronto.
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As of October 2026
Machine learning for health at IMES
Lehman is a Research Scientist at MIT's Institute for Medical Engineering and Science and a Principal Investigator leading the project Learning Optimal Dynamic Treatment Strategies from Observational Health Data. In May 2026, the paper SL-S4Wave, on self-supervised learning of physiological waveforms with structured state space models, is accepted at TMLR, and the group's postdoc opening is supported by a four-year NIH grant for 2025–2029.
Career
- NowMassachusetts Institute of TechnologyResearch Scientist
- IBM ResearchProject Lead
Education
- Georgia Institute of TechnologyMaster's degree
- Massachusetts Institute of TechnologyPhD
Sources and credits
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- Li-wei H. Lehman
- A Physiological Time Series Dynamics-Based Approach to Patient Monitoring and Outcome Prediction
- Deep-learning technique predicts clinical treatment outcomes
- MIMIC-IV, a freely accessible electronic health record dataset
- VTaC: A Benchmark Dataset of Ventricular Tachycardia Alarms from ICU Monitors
- MIT Research Positions in Machine Learning for Health