Jeanette P. Schmidt
Also known as Jeanette Schmidt
Jeanette P. Schmidt is a computer scientist whose work spans combinatorial algorithms, computational biology and the genotype-calling methods behind large biobank studies. After a 1986 PhD in computer science at the Weizmann Institute of Science, she joined Polytechnic University in Brooklyn in 1989, where she served as an associate professor, then moved to Incyte Genomics in 1997 and rose to Vice President of Bioinformatics Research and Development. From 2004 to 2010 she directed Stanford's NIH-funded Simbios center for physics-based simulation, and in September 2010 she became Vice President of Informatics at Affymetrix, where she sat on the steering committee of the 1000 Genomes Project in 2015. As Head of Bioinformatics at Thermo Fisher Scientific, she supervised work on the Rare Heterozygous Adjusted algorithm, published in 2022, which improves rare-variant calls on UK Biobank array data.
Timeline
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1986
A Weizmann computer science PhD
After a B.Sc. in mathematics and statistics at the Hebrew University in Jerusalem, she earns an M.S. in applied mathematics and, in 1986, a Ph.D. in computer science at the Weizmann Institute of Science in Rehovot, Israel.
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1989
Associate professor at Polytechnic
After visiting professorships at Rutgers University and New York University's Courant Institute, she joins the Computer Science Department at Polytechnic University in Brooklyn in 1989, where she serves as an associate professor. Her research focuses on computational biology, bioinformatics and combinatorial algorithms. On sabbatical, she spends a year in Stanford's Department of Biochemistry and Section for Medical Informatics with a National Science Foundation grant for Visiting Professors.
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1997–2004
Bioinformatics at Incyte Genomics
She joins Incyte Genomics in 1997 and eventually serves as Vice President of Bioinformatics Research and Development, leading bioinformatics research, operations and product development.
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2004–2010
Executive director of Simbios
In 2004, she becomes executive director of Simbios, the National Center for Physics-Based Simulation of Biological Structures at Stanford University, newly funded by an NIH Roadmap grant. She directs Simbios until 2010.
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2007–2008
Allosteric pathways in myosin
In 2007, with Russ B. Altman and James A. Spudich, she publishes a computational method that predicts pathways of conserved residues carrying allosteric communication in myosin, using distance constraints and evolutionary data. In 2008, she is first author of an overview of Simbios and its open-source Simbody library for multibody simulation.
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September 2010
Vice president at Affymetrix
In September 2010, she becomes Vice President of Informatics at Affymetrix.
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2015
The 1000 Genomes Project
In 2015, she sits on the steering committee of the 1000 Genomes Project and leads its Affymetrix group as principal investigator. The project's final paper reconstructs the genomes of 2,504 individuals from 26 populations using low-coverage whole-genome sequencing, deep exome sequencing and dense microarray genotyping.
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2020–2022
Head of bioinformatics at Thermo Fisher
In 2020, at Thermo Fisher Scientific in Santa Clara, she coauthors the design of the Million Veteran Program's MVP 1.0 custom Axiom array, which yields quality-controlled genotypes for 459,777 veterans. In 2022, she supervises work on the Rare Heterozygous Adjusted (RHA) algorithm, which improves rare-variant calls on UK Biobank Axiom array data. She serves as Head of Bioinformatics at Thermo Fisher Scientific.
Career
- 2010–2022Thermo Fisher ScientificVice President of Informatics, Head of Bioinformatics
- 2004–2010Stanford UniversitySabbatical, Executive Director
- From 1989Polytechnic UniversityAssociate Professor
- Rutgers UniversityVisiting Professor
- Courant Institute of Mathematical SciencesVisiting Professor
Education
- 1986Weizmann Institute of ScienceM.S. in applied mathematics
- Hebrew University of JerusalemB.Sc.
Sources and credits
Photo: We have no published photo of Jeanette P. Schmidt yet. Send us a free-licensed photo.
- User:Jeanette Schmidt - Genome Analysis Wiki
- The Simbios National Center: Systems Biology in Motion - PMC
- Bio-X Stanford University
- SimTK: Jeanette Schmidt
- Predicting allosteric communication in myosin via a pathway of conserved residues - PMC
- A global reference for human genetic variation | Nature
- Genotyping Array Design and Data Quality Control in the Million Veteran Program - PMC
- Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array data - PMC
- Interviews | Thermo Fisher Scientific

