Researcher

Jeanette P. Schmidt

Also known as Jeanette Schmidt

Jeanette P. Schmidt is a computer scientist whose work spans combinatorial algorithms, computational biology and the genotype-calling methods behind large biobank studies. After a 1986 PhD in computer science at the Weizmann Institute of Science, she joined Polytechnic University in Brooklyn in 1989, where she served as an associate professor, then moved to Incyte Genomics in 1997 and rose to Vice President of Bioinformatics Research and Development. From 2004 to 2010 she directed Stanford's NIH-funded Simbios center for physics-based simulation, and in September 2010 she became Vice President of Informatics at Affymetrix, where she sat on the steering committee of the 1000 Genomes Project in 2015. As Head of Bioinformatics at Thermo Fisher Scientific, she supervised work on the Rare Heterozygous Adjusted algorithm, published in 2022, which improves rare-variant calls on UK Biobank array data.

Works
64
Badges

Publication numbers from OpenAlex, as of 22 October 2026. Citations and h-index are hidden because this OpenAlex record may be incomplete or mix in other authors.

Timeline

  1. 1986

    A Weizmann computer science PhD

    After a B.Sc. in mathematics and statistics at the Hebrew University in Jerusalem, she earns an M.S. in applied mathematics and, in 1986, a Ph.D. in computer science at the Weizmann Institute of Science in Rehovot, Israel.

  2. 1989

    Associate professor at Polytechnic

    After visiting professorships at Rutgers University and New York University's Courant Institute, she joins the Computer Science Department at Polytechnic University in Brooklyn in 1989, where she serves as an associate professor. Her research focuses on computational biology, bioinformatics and combinatorial algorithms. On sabbatical, she spends a year in Stanford's Department of Biochemistry and Section for Medical Informatics with a National Science Foundation grant for Visiting Professors.

  3. 1997–2004

    Bioinformatics at Incyte Genomics

    She joins Incyte Genomics in 1997 and eventually serves as Vice President of Bioinformatics Research and Development, leading bioinformatics research, operations and product development.

  4. 2004–2010

    Executive director of Simbios

    In 2004, she becomes executive director of Simbios, the National Center for Physics-Based Simulation of Biological Structures at Stanford University, newly funded by an NIH Roadmap grant. She directs Simbios until 2010.

  5. 2007–2008

    Allosteric pathways in myosin

    In 2007, with Russ B. Altman and James A. Spudich, she publishes a computational method that predicts pathways of conserved residues carrying allosteric communication in myosin, using distance constraints and evolutionary data. In 2008, she is first author of an overview of Simbios and its open-source Simbody library for multibody simulation.

  6. September 2010

    Vice president at Affymetrix

    In September 2010, she becomes Vice President of Informatics at Affymetrix.

  7. 2015

    The 1000 Genomes Project

    In 2015, she sits on the steering committee of the 1000 Genomes Project and leads its Affymetrix group as principal investigator. The project's final paper reconstructs the genomes of 2,504 individuals from 26 populations using low-coverage whole-genome sequencing, deep exome sequencing and dense microarray genotyping.

  8. 2020–2022

    Head of bioinformatics at Thermo Fisher

    In 2020, at Thermo Fisher Scientific in Santa Clara, she coauthors the design of the Million Veteran Program's MVP 1.0 custom Axiom array, which yields quality-controlled genotypes for 459,777 veterans. In 2022, she supervises work on the Rare Heterozygous Adjusted (RHA) algorithm, which improves rare-variant calls on UK Biobank Axiom array data. She serves as Head of Bioinformatics at Thermo Fisher Scientific.

Career

  1. 2010–2022Thermo Fisher ScientificVice President of Informatics, Head of Bioinformatics
  2. 2004–2010Stanford UniversitySabbatical, Executive Director
  3. From 1989Polytechnic UniversityAssociate Professor
  4. Rutgers UniversityVisiting Professor
  5. Courant Institute of Mathematical SciencesVisiting Professor

Education

  1. 1986Weizmann Institute of ScienceM.S. in applied mathematics
  2. Hebrew University of JerusalemB.Sc.

Sources and credits

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  1. User:Jeanette Schmidt - Genome Analysis Wiki genome.sph.umich.edu. Checked 20 October 2026.
  2. The Simbios National Center: Systems Biology in Motion - PMC pmc.ncbi.nlm.nih.gov. Checked 20 October 2026.
  3. Bio-X Stanford University web.stanford.edu. Checked 20 October 2026.
  4. SimTK: Jeanette Schmidt simtk.org. Checked 20 October 2026.
  5. Predicting allosteric communication in myosin via a pathway of conserved residues - PMC pmc.ncbi.nlm.nih.gov. Checked 20 October 2026.
  6. A global reference for human genetic variation | Nature nature.com. Checked 20 October 2026.
  7. Genotyping Array Design and Data Quality Control in the Million Veteran Program - PMC pmc.ncbi.nlm.nih.gov. Checked 20 October 2026.
  8. Novel genotyping algorithms for rare variants significantly improve the accuracy of Applied Biosystems™ Axiom™ array genotyping calls: Retrospective evaluation of UK Biobank array data - PMC pmc.ncbi.nlm.nih.gov. Checked 20 October 2026.
  9. Interviews | Thermo Fisher Scientific thermofisher.com. Checked 20 October 2026.