Jiaxin Shi
Jiaxin Shi is a machine-learning researcher whose work spans probabilistic inference, sequence modeling, and generative modeling. He earned computer science degrees at Tsinghua and worked as a postdoctoral researcher in Microsoft Research New England's Machine Learning and Statistics group. His 2022 work on variance-reduced gradient estimation won a NeurIPS Outstanding Paper Award; later papers introduced a multiresolution sequence model and a learned ordering for molecular generation. In 2026, he coauthored AlphaProtein Novo, a diffusion system for designing new-to-nature enzymes. As of October 2026, he is a research scientist at Meta SuperIntelligence Labs; he previously worked as a research scientist at Google DeepMind.
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Timeline
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2015–2020
A Tsinghua computer science PhD
He earns a B.E. in Computer Science and Technology at Tsinghua University in 2015 and completes a Ph.D. in the same field in 2020 under Jun Zhu.
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2021
A Microsoft Research postdoc
In 2021, he works as a postdoctoral researcher in the Machine Learning and Statistics group at Microsoft Research New England. His research develops theory and scalable algorithms for inference in probabilistic machine learning.
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2022
A NeurIPS Outstanding Paper
In 2022, he coauthors Gradient Estimation with Discrete Stein Operators with Yuhao Zhou, Jessica Hwang, Michalis K. Titsias, and Lester W. Mackey. The paper uses discrete Stein operators to build variance reduction control variates for the REINFORCE leave-one-out estimator, and it wins a NeurIPS Outstanding Paper Award.
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2023
Multiresolution sequence modeling
In 2023, his ICML paper with Ke Alexander Wang and Emily B. Fox introduces MultiresLayer, a wavelet-inspired sequence-modeling block. Shared filters across dilated causal convolutions let it capture multiscale trends in sequential data.
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2025
Learning molecular generation order
In 2025, he coauthors Learning-Order Autoregressive Models with Application to Molecular Graph Generation. The model learns context-dependent generation orders and is evaluated on the QM9 and ZINC250k molecular-graph benchmarks.
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2026
AlphaProtein Novo enzyme design
In 2026, his work includes AlphaProtein Novo, a joint continuous and masked diffusion system for designing new-to-nature enzymes.
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2026
Area chair at ICML and AISTATS
In 2026, he serves as an area chair for ICML and AISTATS.
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As of October 2026
Research at Meta
As of October 2026, he is a research scientist at Meta SuperIntelligence Labs. He previously worked as a research scientist at Google DeepMind. His research interests include generative and algorithmic modeling, variational inference, sampling, gradient estimation, and score-based modeling.
Career
- NowMeta Superintelligence LabsResearch Scientist
- From 2021Microsoft ResearchPostdoctoral Researcher
- Google DeepMindResearch Scientist
Education
- 2020Tsinghua UniversityB.E. and PhD
Sources and credits
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- Sampling with Mirrored Stein Operators (Talk by Jiaxin Shi, Microsoft Research New England) | Center for Advanced Intelligence Project
- Announcing the NeurIPS 2022 Awards
- Gradient Estimation with Discrete Stein Operators
- Sequence Modeling with Multiresolution Convolutional Memory
- Learning-Order Autoregressive Models with Application to Molecular Graph Generation
- Homepage - Jiaxin Shi
- Jiaxin Shi



