Ingie Hong

Timeline

1. 2007

   Fear extinction research in Seoul

   In 2007, Ingie Hong is among the coauthors of 'Amygdala depotentiation and fear extinction' in PNAS, with Sukwoo Choi as corresponding author at the School of Biological Sciences, Seoul National University. The study in rats gives strong evidence that AMPA receptor removal at excitatory synapses in the lateral amygdala underlies fear extinction.

2. August 2013

   Fear renewal in Nature Neuroscience

   At Seoul National University in August 2013, Hong coauthors a Nature Neuroscience paper showing that fear renewal requires GluA1 phosphorylation at serine 831 in the lateral amygdala.

3. 2015

   C9orf72 and nucleocytoplasmic transport

   With Richard L. Huganir, Jonathan C. Grima, Shu-Ling Chiu, Thomas E. Lloyd and Jeffrey D. Rothstein in the Department of Neuroscience at Johns Hopkins, Hong coauthors the 2015 Nature paper 'The C9orf72 repeat expansion disrupts nucleocytoplasmic transport.'

4. 2016

   OGT and feeding in Science

   In 2016, a Science paper from the Solomon H. Snyder Department of Neuroscience at the Johns Hopkins University School of Medicine lists Hong and Richard Huganir among its authors. The paper shows that deleting the enzyme OGT from αCaMKII-positive neurons in adult mice causes obesity from overeating, traced to the paraventricular nucleus of the hypothalamus.

5. 2020

   A kinase biosensor for awake mice

   Alongside equal-contribution authors Jin-Fan Zhang and Bian Liu in 2020, Hong coauthors a Nature Chemical Biology paper that reports ExRai-AKAR2, a second-generation PKA activity reporter. Imaging the visual cortex of awake mice with the sensor shows neuronal PKA activity that forced locomotion rapidly recruits.

6. October 2024

   PV neuron selectivity in Nature

   Nature publishes 'Calcium-permeable AMPA receptors govern PV neuron feature selectivity' in October 2024, with Hong, an instructor in neuroscience at Johns Hopkins, as first author and Richard Huganir as senior author. Replacing calcium-permeable AMPA receptors in PV interneurons with calcium-impermeable ones increases their orientation selectivity in the visual cortex.

7. December 2025

   Syngap1 study from Hopkins and KAIST

   In December 2025, Nature Communications publishes 'Syngap1 and the development of murine neocortical progenitor cells,' coauthored by Hong with Soraia Barão, Yijun Xu, Ulrich Müller and Richard Huganir. The paper lists Hong at both the Department of Neurology at Johns Hopkins and the Department of Biological Sciences at KAIST in Daejeon, Korea. In mice, neocortical progenitors and their cellular output stay unchanged by Syngap1 absence or haploinsufficiency.

8. As of October 2026

   Assistant professor at KAIST

   Hong is an assistant professor in KAIST's Department of Biological Sciences, where the Quantitative Intelligence Lab lists artificial intelligence and computational neuroscience among its research areas. The KAIST AX College of AI lists Hong as an adjunct professor with the research area Intellectual Disability / Physical AI in Neuroscience. The lab works from Daejeon, Korea, on intellectual disabilities, with the goal of merging molecular biology, systems neuroscience, and computational modeling to revolutionize treatments for brain disorders and inspire advanced AI.