Synho Do
Synho Do is a medical imaging researcher whose work applies machine learning to radiology. He coauthored a 2012 CT algorithm for measuring pneumothorax, studied training-set size for medical image classification in 2015, and helped develop a fully automated bone-age assessment system in 2017. In 2019, he coauthored SinoNet, which reads CT sinograms without image reconstruction; in February 2026, he coauthored a framework for setting operational safety policies for clinical AI. As of October 2026, he is an assistant professor of radiology at Harvard Medical School and directs MGH's Laboratory of Medical Imaging and Computation.
- Now at
- Harvard University and Mass General Brigham
- Works
- 105
- Citations
- 5,817
- h-index
- 31
Publication numbers from OpenAlex, as of 27 October 2026.
Timeline
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2012
Pneumothorax analysis on CT
In 2012, he coauthors an automated algorithm to quantify pneumothorax on multidetector CT images. It combines two-dimensional and three-dimensional processing to reduce processing time by two-thirds.
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2015
Medical-image training data
In 2015, he coauthors a study on how much data medical-image classification needs. The team trains a convolutional neural network on six training-set sizes and tests it on 6,000 CT images.
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2017
Automated bone-age assessment
In 2017, he coauthors a fully automated deep-learning system for bone-age assessment. Its pipeline segments a region of interest, standardizes and preprocesses radiographs, and performs bone-age assessment.
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2019
SinoNet reads CT sinograms
In 2019, he coauthors SinoNet, a convolutional neural network that processes CT sinograms without first reconstructing images. The team evaluates it for anatomy recognition and intracranial hemorrhage detection.
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February 2026
Operational safety for clinical AI
In February 2026, he coauthors the Safety-Aware Receiver Operating Characteristic (SA-ROC) framework, which combines analytical signals into an operational directive for clinical AI.
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As of October 2026
Radiology and AI at Harvard
As of October 2026, he is an Assistant Professor of Radiology at Harvard Medical School and directs the Laboratory of Medical Imaging and Computation at Massachusetts General Hospital.
Career
- NowHarvard UniversityAssistant Professor of Radiology
- NowMass General BrighamDirector, Laboratory of Medical Imaging and Computation
Sources and credits
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- Automated Quantification of Pneumothorax in CT
- How much data is needed to train a medical image deep learning system to achieve necessary high accuracy?
- Fully Automated Deep Learning System for Bone Age Assessment
- Machine Friendly Machine Learning: Interpretation of Computed Tomography Without Image Reconstruction
- Defining operational safety in clinical artificial intelligence systems
- Synho Do, Ph.D. | Mass General Research Institute
- Affiliate Faculty - Kempner Institute